CR1

CR1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1GKG, 1GKN, 1PPQ, 2Q7Z, 2MCY, 2MCZ, 5FO9
Dynodwyr
Cyfenwau	CR1, C3BR, C4BR, CD35, KN, complement component 3b/4b receptor 1 (Knops blood group), complement C3b/C4b receptor 1 (Knops blood group)
Dynodwyr allanol	OMIM: 120620 HomoloGene: 55474 GeneCards: CR1
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• virus receptor activity; • complement component C3b receptor activity; • complement component C4b receptor activity; • complement component C3b binding; • complement component C4b binding;
Cydrannau o'r gell	• integral component of membrane; • bilen; • Cellbilen; • integral component of plasma membrane; • cell surface; • extracellular exosome; • secretory granule membrane; • ficolin-1-rich granule membrane;
Prosesau biolegol	• negative regulation of complement activation, classical pathway; • immune system process; • positive regulation of serine-type endopeptidase activity; • negative regulation of complement activation, alternative pathway; • complement activation, classical pathway; • viral entry into host cell; • GO:0022415 viral process; • negative regulation of serine-type endopeptidase activity; • regulation of complement activation; • complement receptor mediated signaling pathway; • innate immune response; • neutrophil degranulation; • regulation of regulatory T cell differentiation;
	Sources:Amigo / QuickGO
Orthologau
	1378
	n/a
	ENSG00000203710
	n/a
	P17927
	n/a
	NM_000573; NM_000651; NM_001381851
	n/a
	NP_000564; NP_000642; NP_001368780
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CR1 yw CR1 a elwir hefyd yn Complement C3b/C4b receptor 1 (Knops blood group) (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q32.2.^[2]

[1] "Human PubMed Reference:".

[2] CR1 - Cronfa NCBI

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